Molekularpathologie Solide Tumoren

TP53 Mutationsanalyse

BRAF

KRAS

PD-L1 (IHC)

MSI

HRR (Homologe Rekombinations Reparatur)

NTRK

ESR1 (Mamma-Ca.)

PIK3CA (Mamma-Ca.)

T790M Resistenz (Lungen-Ca.)

NGS-Panel (Lungen-Ca.)

EGFR Exon 18/19/20/21

ALK/ROS Translokationen

NGS-Panel (inklusive EGFR, BRAF, ALK, ROS1, RET, MET, STK11, KRAS, NRAS, TP53, HER2)

BRCA1 large rearrangements (MLPA)

NGS-Panel (inklusive BRCA1, BRCA2)

NGS-Panel (inklusive BRCA1, BRCA2, CHEK2, FANCC, MSH2, MSH6, RAD51, TP53)

NGS-Panel (inklusive BRCA1, BRCA2, PIK3CA)

BRCA1 large rearrangements (MLPA)

NGS-Panel (inklusive BRCA1, BRCA2)

NGS-Panel (inklusive EGFR, ALK, BRCA1, BRCA2, KRAS, BRAF, APC)

KRAS Exon 2/3/4

NRAS Exon 2/3/4

BRAF V600E

Mikrosatelliten Instabilität (MSI)

HER2 (IHC)

BRAF V600E/K und Exon 15

NRAS Codon 61

KIT Exon 11/13/17

NGS-Panel (inklusive BRAF, NRAS, KIT, MAP2K1, MAP2K2, RAC1)

GNA11/GNAQ Codon 209

KIT Exon 9/11/13/17

KIT Exon 13/14 (TKI-Resistenz)

PDGFRA Exon 12/18

IDH1/IDH2

MGMT

RET

MECT1-MAML2 t(11;19)(q21;p13)

FOXL2 C402G