Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC
Anti-angiogenic, vascular endothelial growth factor (VEGF)
Volz C, et al. Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC. Cell Rep 2020 Apr 28;31(4):107568. doi: 10.1016/j.celrep.2020.107568
Immunophenotyping of the PD-L1-positive cells in angioimmunoblastic T cell lymphoma and Hodgkin disease
Angioimmunoblastic T-cell lymphoma, Angioimmunoblastisches T-Zell-Lymphom, Hodgkin lymphoma, HodgkinLymphom, Ligand PD-L1, Receptor PD-1, Rezeptor PD-1
Tiemann M, et al. Immunophenotyping of the PD-L1-positive cells in angioimmunoblastic T cell lymphoma and Hodgkin disease. BMC Res Notes 2020 Mar 7;13(1):139. DOI: 10.1186/s13104-020-04975-w
TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC
EGFR, NSCLC, TKI, TP53
Roeper J, et al. TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC. Oncotarget 2020 Jan 21;11(3):250-264. doi: 10.18632/oncotarget.27430
ALK immunohistochemistry positive, FISH negative NSCLC is infrequent, but associated with impaired survival following treatment with crizotinib
ALK, ALK Translokation, anaplastic lymphoma kinase (ALK) rearrangement, fluorescence in situ hybridisation (FISH), Fluoreszenz in situ Hybridisierung (FISH), Immunhistochemie, immunohistochemistry, non small cell lung cancer (NSCLC)
Thunnissen E, et al. ALK immunohistochemistry positive, FISH negative NSCLC is infrequent, but associated with impaired survival following treatment with crizotinib. Lung Cancer 2019 Dec;138:13-18. doi: 10.1016/j.lungcan.2019.09.023
Mast cell chymase: morphofunctional characteristics
Chymase, Mast cells, Mastzelle
Atiakshin D, et al. Mast cell chymase: morphofunctional characteristics. Histochem Cell Biol 2019 Oct;152(4):253-269. DOI: 10.1007/s00418-019-01803-6
Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial
Lung cancer, NSCLC, ROS1, Targeted treatment, TP53, zielgerichtete Therapie
Michels S, et al. Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial. J Thorac Oncol 2019 Jul;14(7):1266-1276. doi: 10.1016/j.jtho.2019.03.020.
Favorable radiation field decrease in gastric marginal zone lymphoma : Experience of the German Study Group on Gastrointestinal Lymphoma (DSGL)
Extended field, Indolent gastric lymphoma, Indolentes Magenlymphom, Involved field, Non-Hodgkin Lymphom, Non-Hodgkin lymphoma, Radiation therapy, Strahlentherapie
Reinartz G, et al. Favorable radiation field decrease in gastric marginal zone lymphoma : Experience of the German Study Group on Gastrointestinal Lymphoma (DSGL). Strahlenther Onkol 2019 Jun;195(6):544-557. doi:10.1007/s00066-019-01446-5
Initial Characterization of Transgenic Mice Overexpressing Human Histamine H2 Receptors
Gergs U, Bernhardt G, Buchwalow IB, Edler H, Fröba J, Keller M, et al. Initial Characterization of Transgenic Mice Overexpressing Human Histamine H2 Receptors. J Pharmacol Exp Ther 2019 Apr;369(1):129-141. doi:10.1124/jpet.118.255711
Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer
acquired resistance, EGFR p.T790M, EGFR Resistenz, Lung cancer, Lungenkrebs, MET amplification, MET Amplifikation, Third-generation EGFR tyrosine kinase inhibitors
Michels S, et al. Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer. JCO Precis Oncol 2019 Mar 27;3. doi: 10.1200/PO.18.00210
Spatial analysis of p63, K5 and K7 defines two groups of progenitor cells that differentially contribute to the maintenance of normal sebaceous glands, extraocular sebaceous carcinoma and benign sebaceous tumors
Basal and luminal keratins, basale and luminale Keratine, p63, Progenitor cells, Sebaceous glands, Sebaceous tumors, Talgdrüsenkarzinom, Vorläuferzellen
Boecker W, et al. Spatial analysis of p63, K5 and K7 defines two groups of progenitor cells that differentially contribute to the maintenance of normal sebaceous glands, extraocular sebaceous carcinoma and benign sebaceous tumors. J Dermatol 2019 Mar;46(3):249-258. doi:10.1111/1346-8138.14765