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Publikationen aus der Diagnostik und Forschung

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Protease Profile of Tumor-Associated Mast Cells in Melanoma

Carboxypeptidasen, Carboxypeptidases, Chymase, Mast cells, Mastzellen, Melanom, Melanoma, Tryptase

Atiakshin D, et al. Protease Profile of Tumor-Associated Mast Cells in Melanoma. Int J Mol Sci 2022 Aug 11;23(16):8930. doi:10.3390/ijms23168930

Pentafluorophosphato-Phenylalanines: Amphiphilic Phosphotyrosine Mimetics Displaying Fluorine-Specific Protein Interactions

Chemical Biology, Chemische Biologie, Drug Development, Medikamentenentwicklung, Pentafluorophosphate, Pentafluorophosphates, Phosphotyrosin Biomimetica, Phosphotyrosine Biomimetics, Protein Tyrosin Phosphatasen, Protein Tyrosine Phosphatases

Accorsi M, et al. Pentafluorophosphato-Phenylalanines: Amphiphilic Phosphotyrosine Mimetics Displaying Fluorine-Specific Protein Interactions. Angew Chem Int Ed Engl 2022 Jun 20;61(25):e202203579. doi:10.1002/anie.202203579

Outcome of Ordinary Polymorphous Adenocarcinomas of the Salivary Glands in Comparison With Papillary and Cribriform Subtypes

adenocarcinoma, molecular pathology

Clausen S, Falk M, Oesterling F, Fehr A, Stang A, Boecker W, et al. Outcome of Ordinary Polymorphous Adenocarcinomas of the Salivary Glands in Comparison With Papillary and Cribriform Subtypes. Anticancer Res 2022 Mar;42(3):1455-1463. doi 10.21873/anticanres.15616

Carboxypeptidase A3-A Key Component of the Protease Phenotype of Mast Cells

Carboxypeptidase A3, Granula, granules, Mast cells, Mastzellen, secretome, secretory pathways, Sekretom, Sekretorische Signalwege, Specific tissue microenvironment, spezifisches Gewebemikromilieu

Atiakshin D, et al. Carboxypeptidase A3-A Key Component of the Protease Phenotype of Mast Cells. Cells 2022 Feb 6;11(3):570. doi:10.3390/cells11030570

TP53 co-mutations as an independent prognostic factor in 2nd and further line therapy- EGFR mutated non-small cell lung cancer IV patients treated with osimertinib

EGFR, metastasiert, metastatic, non small cell lung cancer (NSCLC), NSCLC, Osimertinib, TP53 co-mutation, TP53 Komutation

Roeper J, et al. TP53 co-mutations as an independent prognostic factor in 2nd and further line therapy- EGFR mutated non-small cell lung cancer IV patients treated with osimertinib. Transl Lung Cancer Res 2022 Jan;11(1):4-13. doi:10.21037/tlcr-21-754

Atrial Giant Cell Myocarditis as a Cause of Heart Failure: Diagnostic Pathway and Successful Treatment

Paitazoglou C, Bergmann MW, Tiemann K, et al. Atrial Giant Cell Myocarditis as a Cause of Heart Failure: Diagnostic Pathway and Successful Treatment. JACC Case Rep. 2022 Jan 5;4(1):66-71. doi:10.1016/j.jaccas.2021.11.007

Liquid Biopsy for Biomarker Testing in Non-Small Cell Lung Cancer: A European Perspective

Malapelle U, Tiseo M, Vivancos A, Kapp J, Serrano MJ, Tiemann M. Liquid Biopsy for Biomarker Testing in Non-Small Cell Lung Cancer: A European Perspective. J. Mol. Pathol. 2021 Aug 18;2(3):255-273. doi:10.3390/jmp2030022

Morbus Castleman – ein seltenes, heterogenes Krankheitsbild

Hoffmann C, Tepel J, Tiemann M. Morbus Castleman – ein seltenes, heterogenes Krankheitsbild. Best Practice Onkologie 2021 Mar 09;16:198-206. doi:10.1007/s11654-021-00300-4

Mucoepidermoid carcinoma of the salivary glands revisited with special reference to histologic grading and CRTC1/3-MAML2 genotyping

CRTC1-MAML2, Gene fusion, Genfusion, Head and neck neoplasms, Kopf-Hals Tumore, Mucoepidermoid carcinoma, Mukoepidermoidkarzinom, Neoplasm grading, Observer variation, Observer-Variabilität

Fehr A, et al. Mucoepidermoid carcinoma of the salivary glands revisited with special reference to histologic grading and CRTC1/3-MAML2 genotyping. Virchows Arch 2021 Nov;479(5):975-985. doi:10.1007/s00428-021-03146-x

MSI testing : What’s new? What should be considered?

DNA mismatch repair, Endometrial carcinoma, Endometriumkarzinom, Immun-Checkpoint-Inhibition, Immune checkpoint inhibitors, Microsatellite instability, Mikrosatelliten-Instabilität, Prognose, Prognosis