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Publikationen aus der Diagnostik und Forschung

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Signaling Pathways in the Pathogenesis of Barrett’s Esophagus and Esophageal Adenocarcinoma

Barrett’s esophagus, Barrett’s Oesophagus, carcinogenesis, dysplasia, Dysplasie, esophageal adenocarcinoma, Inflammatorische Signalwege, inflammatory signaling pathways, intestinal metaplasia, Intestinale Metaplasie, Karzinogenese, mutational load, Mutationslast, oesophageales Adenokarzinom, p53

Maslenkina K, et al. Signaling Pathways in the Pathogenesis of Barrett’s Esophagus and Esophageal Adenocarcinoma. Int J Mol Sci 2023 May 26;24(11):9304. doi:10.3390/ijms24119304

Noninferiority of Artificial Intelligence–Assisted Analysis of Ki-67 and Estrogen/Progesterone Receptor in Breast Cancer Routine Diagnostics

digital pathology, digitale Pathologie, Mamma carcinoma

Abele N, Tiemann K, Krech T, Wellmann A, Schaaf C, Länger F, et al. Noninferiority of Artificial Intelligence–Assisted Analysis of Ki-67 and Estrogen/Progesterone Receptor in Breast Cancer Routine Diagnostics. Mod Panthol 2023 Mar;36(3):100033. doi:10.1016/j.modpat.2022.100033

Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect

Brandwunde, burn wound, fibröse extrazelluläre Matrix, fibrous extracellular matrix, Haut, Mast cells, Mastzellen, molecular hydrogen, molekularer Wasserstoff, Regeneration, Skin

Atiakshin D, et al. Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect. Pharmaceuticals (Basel) 2023 Feb 24;16(3):348. doi:10.3390/ph16030348

Response of an HER2-Mutated NSCLC Patient to Trastuzumab Deruxtecan and Monitoring of Plasma ctDNA Levels by Liquid Biopsy

disease monitoring, HER2 Mutation, Krankheitsmonitoring, Liquid Biopsy, Trastuzumab Deruxtecan

Falk M, et al. Response of an HER2-Mutated NSCLC Patient to Trastuzumab Deruxtecan and Monitoring of Plasma ctDNA Levels by Liquid Biopsy. Curr Oncol 2023 Jan 30;30(2):1692-1698. doi:10.3390/curroncol30020130

The Remodeling of Dermal Collagen Fibrous Structures in Mice under Zero Gravity: The Role of Mast Cells

collagen fibers, extracellular matrix,, extrazelluläre Matrix, Fibroblasten, fibroblasts, Haut, Kollagenfasern, Mast cells, Mastzellen, Schwerelosigkeit, Skin, zero gravity

Shishkina V, et al. The Remodeling of Dermal Collagen Fibrous Structures in Mice under Zero Gravity: The Role of Mast Cells. Int J Mol Sci 2023; Jan 18;24(3):1939. doi: 10.3390/ijms24031939

Genetic alterations affecting the C-terminus of cyclin D1 are recurrent events in mantle cell lymphoma

Laccarino I, et al. Genetic alterations affecting the C-terminus of cyclin D1 are recurrent events in mantle cell lymphoma. Histopathology 2023 Jan;82(2):371-373. doi:10.1111/his.14815. Epub 2022 Oct 13

Fluorescence in situ hybridization test for detection of endometrial carcinoma cells by non‐invasive vaginal swab

Endometrial carcinoma, Endometriumkarzinom, Fluoreszenz in situ Hybridisierung (FISH)

Weimer J, Hüttmann M, Nusilati A, Andreas S, Röseler J, Tribian N, et al. Fluorescence in situ hybridization test for detection of endometrial carcinoma cells by non‐invasive vaginal swab. J Cell Mol Med. 2023 Jan 10;27(3):379-391. doi:10.1111/jcmm.17658

A Formylglycine-Peptide for the Site-Directed Identification of Phosphotyrosine-Mimetic Fragments

Formylglycin, formylglycine, fragment ligation, fragment-based drug discovery, Fragment-basierte Arzeimittelforschung, Fragmentligation, phosphatase inhibitors, Phosphataseinhibitoren, site-directed screening

Tiemann M, et al. A Formylglycine-Peptide for the Site-Directed Identification of Phosphotyrosine-Mimetic Fragments. Chemistry 2022 Oct 12;28(57):e202201282. doi:10.1002/chem.202201282

Recent Advances in Castleman Disease

Castleman disease, HHV-8, Morbus Castleman, Multicentric CD, Multizentrisches CD, Siltuximab, Unicentric CD, Unizentrisches CD

Hoffmann C, et al. Recent Advances in Castleman Disease. Oncol Res Treat 2022;45(11):693-704. doi:10.1159/000526640. Epub 2022 Oct 11

Acquired G2032R Resistance Mutation in ROS1 to Lorlatinib Therapy Detected with Liquid Biopsy

G2032R, Liquid Biopsy, Lorlatinib, NSCLC, resistance mutation, Resistenzmutation, ROS1

Jóri, B.; Falk, M.; Hövel, I.; Weist, P.; Tiemann, M.; Heukamp, L.C.; Griesinger, F. Acquired G2032R Resistance Mutation in ROS1 to Lorlatinib Therapy Detected with Liquid Biopsy. Curr. Oncol. 2022, 29, 6628–6634. https://doi.org/10.3390/ curroncol29090520